Ruby H. Barghini, MD, Assistant Professor of Clinical Psychiatry and Behavioral Science and Director of the Psychiatry Residency Program at the Lewis Katz School of Medicine at Temple University, and Holly Betterly, MD, Psychiatry Resident, provided perspective for the Psychiatric Times about apetamin, a syrup that contains cyproheptadine, lysine and B vitamins and has been promoted on social media as a weight gain supplement.