Media Outlets Highlight New Study Led by Dr. Walter Koch and Lewis Katz School of Medicine Researchers on GRK5, p53 and Cardiac Hypertrophy

In a new study published online in the Journal of the American College of Cardiology: Basic to Translational Science, Lewis Katz School of Medicine researchers show that GRK5 (the G protein-coupled receptor kinase 5 signaling molecule), which is known to influence cardiac hypertrophy, promotes maladaptive cardiac remodeling and progressive decline in heart function by keeping heart cells alive. Walter J. Koch, PhD, W.W. Smith Endowed Chair in Cardiovascular Medicine, Professor and Chair of the Department of Cardiovascular Sciences, and Director of the Center for Translational Medicine at the Katz School of Medicine at Temple University, is the corresponding author. Alessandro Cannavo, PhD, Associate Professor in the Department of Translational Medical Sciences at Federico II University of Naples, is the senior author on the study. Dr. Cannavo started the study while a fellow in Dr. Koch’s lab. Medical Xpress and Scienmag highlighted the news.