PLS Natural History Study

The goal of the PLS Natural History study is to advance the current research state of PLS by generating collecting clinical data and biological samples over time to understand the natural progression of the disease. This will advance development of future research and clinical trials. If you consent to participate in this study, you will have study visits every 3 months for 1 year and a final study visit at 2 years (24 months). Visits 2 (3 month follow up), 4 (month 9) and 6 (month 24) will occur over the phone and visits 3 (month 6) and 5 (month 12) will be mostly in-person. In addition to collection of clinical data relevant to PLS an electromyography (EMG) test will be performed at visit 5 (month 12).