Often, there are no symptoms of tricuspid valve regurgitation. As a patient ages and tricuspid disease worsens, the continual backflow of blood puts extra pressure on the right atrium and weakens the heart leading to fatigue, shortness of breath, and a fluttering sensation in the neck. Later complications may include heart failure (e.g., lung congestion, fatigue at rest, fainting, swollen feet and ankles), chest pain, arrhythmias or heart attack.